Scientific Update March 2003
Thank you very much for your interest in Body Language Vitamin Company's Scientific Formulas
This is a scientific update as I had promised. It is also to thank you for visiting our website and or benefiting from our state of the art supplements. This update will keep you informed with important new research information.
I welcome you to visit our site Body Language Vitamin Company and use our Body Mass Index Calculator and to take our copyrighted health scan. These health tools are free to you and provide important information regarding your wellness.
Postmenapausal Hormone Replacement Therapy what you need to know (if you are a man, pass this on to any women in your life)
38% of postmenopausal women in the USA are using hormone replacement therapy (HRT). Most often, women are prescribed either estrogen alone or estrogen with progestin. The earlier science suggested that HRT would reduce the risk of osteoporosis, heart disease, stroke, hot flashes etc. HRT continues to be prescribed at a cost of more than 1 billion dollars/year (Hemminki et al BMJ 1997). Interestingly, estrogen used to be prescribed alone, however scientist found that there was a significant increase in the risk of endometrial cancer and therefore Dr's began recommending the addition of progestins in women with an intact uterus (if you did not have a uterus, there was no reason to start the progestins) (Hogervorst et al Neuroscience 2000).
As early as 1996 the evidence from the second US Preventive Services Task Force (UPSTF) suggested that the evidence was equivocal (did not support or go against) the use of HRT. Essentially this meant that there probably was no real reason to continue to recommend HRT (most of you were not made aware of this and the prescriptions continued to roll out) (US preventive Services Task Force Guide to Clinical Preventive Services 2nd ed 1996).
In a recent detailed scientific review the following information was identified:
Heart disease: 43 studies were reviewed. The main outcome was that there was an increased risk for nonfatal heart attacks (~ 1.32 the risk) (Writing group for the Women's Health Initiative Investigators JAMA 2002). Another study with 16,608 postmenapausal women between the ages of 50-79 using both estrogen and progestin had a 29% increased rate of heart disease (Writing Group for the Women's Health Initiative Investigators JAMA 2002). In the HERS II study the final recommendations were that HRT has no place for reducing the risk of heart disease (a long held concept) (Grady et al JAMA 2002).
Stroke: A meta analysis of nine major studies showed that the likelihood of developing a stroke was significantly increased among people who had ever used HRT. In the study with 16,608 women, they found a startling 41% increased risk for stroke.
Blood Clots: There was a 2-3.5 times higher risk of developing a blood clot. This risk was highest in the first year of use.
Osteoporosis: There was a 27% reduced risk of fractures (based upon a review of 22 major studies).
Breast Cancer: This is a bit more confusing to understand, but I will attempt to explain. 14/18 studies reported no increase in breast cancer occurrence with "ever use" of Estrogen. However, they found that current use of estrogen is associated with a statistically significant increased risk of breast cancer (isn't science interesting!). The bottom line is if you are a current user of estrogen + progestin, it appears as if you have an increased risk of developing breast cancer. This risk is worse the longer you are on HRT (please remember, science often changes its opinions, and some things that were believed to be true get disproved at a later date).
Endometrial Cancer: There was an increased risk of this cancer type in most studies.
Ovarian Cancer: In a study of 44,241 postmenopausal women using HRT there was a 2.6 times the risk of developing ovarian cancer than those people not using HRT (Lacey et al JAMA 2002)
Colon Cancer: Guess what here is one place we win! People on HRT had a 20% reduced risk for developing colon cancer.
Dementia: This remains controversial, however there appeared to be a possible reduced risk of Alzheimer's disease and other cognitive disorders.
Gall Bladder Problems: There was a significant increased risk of gall bladder difficulties in patients on HRT.
Moral of the story: It would seem obvious that we should never start patients on HRT and that people taking it should stop. Well, maybe true, maybe not. There were several studies that suggested that the risk for heart disease while increased early on in therapy, might decrease over time. This coupled with reduced rates of colon cancer, fractures, and menapause symptoms led Dr's to seriously consider: "don't start, don't stop" (Petitti JAMA 2002). That is if you have never been on HRT, don't bother initiating therapy and if you have been on it for more than 1-2 years, probably shouldn't stop it.
All of the above information was gleaned from multiple sources including: (Nelson et al JAMA 2002; Writing group for the Women's Health Initiative Investigators JAMA 2002; Petitti JAMA 2002; Lacey et al JAMA 2002; Grady et al JAMA 2002)
What can you do about it the hot flashes, the dryness of mucosal surfaces short of HRT etc? Well quite a bit actually and this will be the basis of our next scientific update, but if you have to have additional information now, please feel free to visit our site and read our Powerpoint presentation on Complementary/Integrative Medicine and Women's issues. You will find this presentation under the Educational Resources Task bar at Body Language Vitamin Company Additionally within 3-4 months we will have the best and safest all-natural supplement created just for you or (if you are a man) the women in your life that are experiencing hot flashes, PMS, mood swings associated with the menstrual cycle or other problems related to hormonal variations.
Colds and flu from traveling on planes?
Is it true that people are more apt to get sick on an airplane? Well logic would dictate that this is the case. You know the routine; you're always in the seat very close to the sneezing, hacking, nose blowing person... never fails. Usually within 24-48 hours you have got their bug. I cannot tell you how many patients tell me that this is the most common way they developed their upper respiratory infection (URI = common cold). Interestingly, Zitter et al did a study on 1100 passengers flying from San Francisco to Denver during January through early April and guess what? They found no evidence that aircraft cabin air recirculation increases the risk for URI symptoms! (Zitter et al JAMA 2002). Ask any flight attendant and most passengers and they would disagree. Newer aircraft recirculate at least 50% of the cabin air to decrease the jets engine output. Although there are high efficiency particulate filters on the plane, its ability to capture viral particles is negligible at best. The above mentioned article admits that the study is limited because of the relatively few numbers of people involved in the study. Furthermore, the findings were "close" and they might have missed a "modest effect"
What can we do about this. First off if this data are correct then no worries, but again, too many people are convinced that they are much more likely to develop a URI after flying. What do I do? Wash my hands frequently and I take two BLV Co proprietary cold and flu formula prior to flying (thousands of other people are doing this successfully as well). This is a formula that I have developed with one of the most famous Hakim's (Herbal Medicine Dr) in Pakistan. We have included only the correct parts of the plant and used the most purest grown ingredients.
Most people do not realize that there are at least nine different subtypes of Echinacea, ie E. purpurea, pallida and angustifolia. According to the German Commission E (the leading text for the medicinal use of herbs), E. purpurea leaf and E.pallida root work to enhance T and B cell function (important cells for healthy immune function), but that other parts of the same plant are ineffective! Additionally, they rate E. Angustifolia as a negative herb. An herb gets a negative rating if it is ineffective, harmful or not enough is known. Most bottles of Echinacea that you purchase in the store are surprisingly the angustifolia form, why? Because those manufacturers are NOT doing their homework and they are likely just trying to save money. At Body Language Vitamin Co we have done our research very carefully, check out our Proprietary Cold and flu Formula. Limited clinical research has shown that this supplement reduces the symptoms of the common cold and shortens duration of the URI to 2-4 days in up to 85% of users. We find this formula to be highly effective. We also have many users that take this prophylactically to flying and they swear by its protective effects (see some of our unsolicited testimonials). If you have an autoimmune disorder (ie Lupus or Juvenile Rheumatoid Arthritis) or if you are taking medicines that would affect your immune system, ie anti-cancer drugs, or medicines to reduce your likelihood of rejecting an organ transplant then you must not take this supplement without first consulting with your physician.
Please note: Body Language Vitamin Co/Michael D. Seidman, MD, FACS reserve all rights to this proprietary information. Any use of this information without the express written consent of BLV Co or Michael D. Seidman, MD is considered a violation of copyright/trademark laws and persons knowingly or unknowingly found guilty of copying or using this information will be punished to the fullest extent of the law.
Body Language Vitamin Companys mission is to promote your health and wellness through responsible lifestyle choices and appropriate supplementation.
I hope you have found this information valuable and helpful. Please feel free to contact me with any questions. I answer all of my emails; please allow 24-72 hours as we get many questions. You can also find many other interesting studies and articles by clicking on Educational Resources (A task bar on the left) at Body Language Vitamin Company
Michael D. Seidman, MD., FACS
B.S. Human Nutrition
CEO-Body Language Vitamin Co
Director of Otologic/Neurotologic Surgery/Henry Ford Health System
Director of Complementary/Integrative Medicine Henry Ford Health System
Office: 248-661-7211 (Henry Ford Health System)
Body Language Office (voice mail) 877-LIVE-FIT
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