Scientific Update December 2003
Thank you for using Body Language Vitamin Company's Scientific Formulas
This is a scientific update as I had promised. It is also to thank you for visiting our website and or benefiting from our state of the art supplements. This update will keep you informed with important new research. I welcome you to visit our site Body Language Vitamin Co and use our Body Mass Index Calculator and to take our copyrighted health scan. These health tools are free to you and provide important information regarding your wellness. I would also encourage you to pass this update on to all of your friends, family and anyone that you love, like or care about.
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Pill
May Reduce Hearing Loss From Noise
Sat Oct 11,
Noise-induced hearing loss is one of the most common occupational diseases and
the second most self-reported occupational illness or injury, the federal
government says. About 10 million Americans have permanent hearing loss from
loud noise, either a long-term exposure or in a sudden burst like an explosion.
And an estimated 30 million people are thought to be exposed to hazardous
levels of noise at work, such as in mining, construction, manufacturing and
agriculture.
"Noise-induced
hearing loss is such a common cause of hearing loss, and we haven't been very
effective in ways to manage it," said Sharon Kujawa,
director of audiology at the Massachusetts Eye and
Ear Infirmary.
Scientists have pursued a variety of approaches toward an ear-fortifying pill.
In 1994, for example, Israeli researchers reported that magnesium supplements
helped military recruits avoid hearing loss over two months of noisy basic
training. These days, much of the work focuses on antioxidants, the chemical
class that most famously includes vitamins C and E.
That's because loud noise doesn't always damage the delicate inner ear
immediately just by brute force. Rather, in most cases it provokes the inner
ear into making harmful oxygen molecules called free radicals. Antioxidants
neutralize free radicals, and the ear naturally has such defenses. But with
enough noise, the ear's antioxidants are overwhelmed.
In that case, damage from the free radicals leads to death of the ear's sound
receptors— hair cells, which convert the mechanical energy of incoming sound
waves into nerve messages to the brain. As hair cells die off, hearing erodes
permanently. So it makes sense to try to build up the ear's antioxidant
defenses as a preventive step, and as a fast treatment
after noise exposure.
Animal experiments in prevention look promising, and "people are getting
very excited about applying this to protection against noise exposure in
humans," Kujawa said.
"I think it's very exciting," said Brenda Lonsbury-Martin,
director of research at the American Speech-Language-Hearing Association.
Antioxidants should work best if given prior to noise exposure, but animal work
suggests it might reduce permanent hearing loss substantially if given within
four to eight hours afterward, said researcher Col. Richard Kopke.
One
pioneer in the field of using antioxidants for hearing has seen
some effect in people. Dr. Michael Seidman of the
A low-carbohydrate as compared with a low-fat diet in severe obesity:
New England J of Med
These authors randomly assigned 132 SEVERLY obese subjects (those with
a body-mass index of 43 or above to a carbohydrate (CHO) restricted diet or a
calorie and fat restricted diet. Only 79
completed the six month study. Their results showed that sugjects
on the low-CHO diet lost more weight than those on the low-fat diet (12.7
+/-18.9 lbs vs 4.2 +/-9.2 respectively…note the second number is the standard
deviation-this was likely large because of the relatively small numbers of
participants). The difference WAS highly statistically significantly different
(p<0.001). They also found an
improvement in the insulin sensitivity and triglycerides levels, but they
suggest caution in the interpretation because of the short duration of the
study. They also advised longer term
outcome studies before they could formally recommend the CHO-restricted diet.
Drink your red wine and prevent hearing loss?
Seidman et al Effects of resveratrol on acoustic trauma-Oto-Head and Neck Surgery J Nov 2003.
This study was designed to test the ability of resveratrol (a powerful antioxidant in red wine) to protect the ears from free radicals. Oxidative stress (free radical damage) is known to cause MANY medical problems from Heart disease and Alzheimer’s disease to Cancer and aging. In this particular study rats were given either 7 weeks of resveratrol (430 mcg/kg) per day whereas the control group received physiologic saline (ie salt water-but balanced to the body). The subjects were exposed to loud noise for 24 hours (the same level as would be seen at a rock concert). The long story short is that animals that were treated with the red-wine extract had much less hearing loss than the animals that drank a placebo (the salt water). Moral of the story (perhaps a bit soon to tell, though Seidman doesn’t think so), is that a glass of red wine a day, might improve your hearing and possibly protect from the stresses of noise and free radicals. What this study does not show, but is currently being studied in Seidman’s lab at Henry Ford Health System is the effect on aging and cognition, and the preliminary studies are looking very positive.
SOY and OTHER phytoestrogens containing compounds MAY be safe in the face of an estrogen sensitive cancer
Phytoestrogen Intake and
Endometrial Cancer Risk Horn-Ross et al J of National Cancer Institute, Vol 95,
No15,
Scientists and clinicians alike have typically recommended AGAINST the use of phytoestrogens (ie constituents of Soy-specifically dadzein and genistein, and black cohosh, wild yam etc) if you were to have an estrogen receptor positive breast cancer (as an example). I have had several conversations with Dr. Mark Messina (a world authority on soy), who had mixed opinions re the safety of phytoestrogen use in the face of certain hormonally mediated cancers. This paper suggests that the danger is probably not present.
Specifically, they note: “Estrogens found in plant foods (ie phytoestrogens), such as isoflavones found in soybeans and lignans found in whole grains, seeds and dried fruit, have shown to LOWER endogenous estrogen levels (Xu et al Cancer Epid. Biomarkers Prev 1998;7:1101-8; Lu et al Cancer Res 2000;60:4112-21; Hutchins et al Nutr Cancer 2001;39:58-65). Phytoestrogens also stimulate the production of sex hormone-binding globulin (SHBG) by the liver…”this leads to reduced amounts of estrogens available for binding with estrogen receptors. Phytoestrogens also bind competitively to estrogen receptors thereby blocking binding by other estrogens. Furthermore because of their weak estrogenic potential (<0.1% of that of estradiol), phytoestrogens DO NOT elicit a strong estrogenic response and thus have an antiestrogenic effect that INHIBITS the growth and proliferation of estrogen-dependent cancer cells (Molteni et al J Nutr 1995;125;751S-6S; Setchell et al Academic Press Limited; 1998 p 315-45).
In a nutshell, it may not be as dangerous as we once thought to use phytoestrogens in the face of an estrogen responsive tumor/cancer.
They concluded (Horn-Ross et al) that their findings support the hypothesis that phytoestrogens intake is associated with reduced risk of endometrial cancer, particularly in postmenopausal women, presumably through antiestrogenic effects.
IS NOW HERE!
If you suffer from the dreaded, monthly symptoms of premenstrual syndrome (PMS), you’re not alone. It is uncomfortable reality for about 75% percent of women who menstruate, with symptoms ranging from anxiety and depression to decreased sex drive. While nobody knows for sure what causes PMS, it is believe to be provoked by the changing levels in estrogen and progesterone during the two week time period before menstruation.
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Menopause support formula (an oral and a topical cream form will be available)
THE ORAL FORM IS NOW AVAILABLE!
If you’re a woman who suffers from symptoms of menopause, you know all too well the great discomfort your changing hormone levels can cause. But what are you to do, especially in the wake of such concerning and confusing reports?
When a huge national Women’s Health Initiative study showed that the estrogen-progestin pill that millions of women were taking to relieve the symptoms of menopause could actually be harmful, including increased risk of heart disease, stroke and cancer, it left many women feeling the risks of hormone replacement therapy outweighed the benefits. But that still doesn’t stop the real and annoying symptoms caused by changes in the estrogen and progesterone levels, including:
Telling a woman that the symptoms of menopause are “only natural” does little to help her discomfort. But if they are natural responses to the changes in your body, doesn’t it make sense to turn to a natural alternative?
There is relief! Body Language Vitamins has created an all-new natural alternative for relieving your symptoms through a doctor-formulated supplement that combines some of the world’s most powerful and effective herbs and extracts known for their ability to relieve women of the symptoms of menopause.
Body Language Vitamin Company’s mission is to promote your health and wellness through responsible lifestyle choices and appropriate supplementation.
I hope you have found this information valuable and helpful. Please feel free to contact me with any questions. I answer all of my emails; please allow 24-72 hours as we get many questions. You can also find many other interesting studies and articles by clicking on Educational Resources (A task bar on the left) at Body Language Vitamin Company
Michael D. Seidman, MD., FACS
B.S. Human Nutrition
CEO-Body Language Vitamin Co
Director of Otologic/Neurotologic Surgery/Henry Ford Health System
Director of Complementary/Integrative Medicine Henry Ford Health System
Office: 248-661-7211 (Henry Ford Health System)
Body Language Office (voice mail) 877-LIVE-FIT
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